Datasets - mapMECFS

Survey of Anti-Pathogen Antibody Levels in ME/CFS

Plasma antibodies to 122 different pathogen antigens were evaluated in a case-control comparison including 103 individuals. The cohort of 59 ME/CFS and 44 healthy controls...
- Plasma
- anti-pathogen
- case-control
- has data file
- proteomics
- serolgy
- sex differences

Urine Metabolomics Exposes Anomalous Recovery after Maximal Exertion in Femal...

Pilot urine metabolomics study that analyzed Metabolon data generated from 10 people with ME/CFS and 8 healthy sedentary controls. All participants are female. Data was compared...
- CPET
- Metabolomics
- Urine
- case-control
- exercise
- has data file

Urine Metabolomics Exposes Anomalous Recovery after Maximal Exertion in Femal...

Pilot urine metabolomics study that analyzed Metabolon data generated from 10 people with ME/CFS and 8 healthy sedentary controls. All participants are female. Data was compared...
- CPET
- Metabolomics
- Urine
- case-control
- exercise
- has data file
- has phenotype file

Altered Fatty Acid Oxidation in Lymphocyte Populations of ME/CFS - flux measu...

Seahorse flux analysis and flow cytometry were performed on case and control immune cell subtypes. PBMCs were separated into NK and CD4 and CD8 T cell populations. The results...
- Seahorse
- case-control
- flow cytometry
- has data file
- has phenotype file
- immune cells
- metabolic profiling

Altered Fatty Acid Oxidation in Lymphocyte Populations of ME/CFS - flow media...

Seahorse flux analysis and flow cytometry were performed on case and control immune cell subtypes. PBMCs were separated into NK and CD4 and CD8 T cell populations. The results...
- Seahorse
- case-control
- flow cytometry
- has data file
- has phenotype file
- immune cells
- metabolic profiling

Cytokine profiling of extracellular vesicles isolated from plasma in myalgic ...

Giloteaux et al. performed a pilot study to investigate the cytokine content of extracellular vesicles (EVs) in ME/CFS. Plasma cytokines were measured in 38 females (19 ME/CFS...
- Cytokine Assay
- Plasma
- case-control
- has data file
- has phenotype file
- publication-adapted

Recovery from Exercise in Persons with ME/CFS

Moore et al. studied 84 people with ME/CFS and 60 controls using a self-reported symptom severity questionnaire. Both female and male participants from three different test...
- case-control
- has phenotype file
- recovery
- self-report
- symptom severity

Multiomic analyses distinguish ME/CFS cases from controls - EV cytokines

As part of a collaborative project with the Center for Solutions for ME/CFS, Ludovic Giloteaux isolated extracellular vesicles (EVs) from 98 (49 ME/CFS and 49 control) Chronic...
- Cytokine Assay
- Plasma
- case-control
- extracellular vesicles
- has data file
- has phenotype file

Cytokine profiling of extracellular vesicles isolated from plasma in myalgic ...

Giloteaux et al. performed a pilot study to investigate the cytokine content of extracellular vesicles (EVs) in ME/CFS. EV cytokines were measured in 37 females (19 ME/CFS and...

Plasma metabolomics reveals disrupted response and recovery following maximal...

Over 1,100 plasma metabolites were measured and analyzed in 60 ME/CFS and 45 healthy control participants. Each cohort consisted of both females and males. This longitudinal...
- CPET
- ChemRICH
- Metabalomics
- MetaboAnalyst
- Metabolon
- case-control
- longitudinal

ME/CFS case-control plasma proteomics (Fully Normalized)

Plasma proteomics of 20 ME/CFS patients and 20 controls containing 4,790 unique human proteins obtained through somalogic's aptamer-based assay.This dataset contains the fully...
- has data file
- has phenotype file
- publication-adapted

Prospective Biomarkers from Plasma Metabolomics of ME/CFS

Adapted from the paper Germain A, Ruppert D, Levine SM, Hanson MR. Prospective Biomarkers from Plasma Metabolomics of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome...
- case-control
- mass spectrometry

Comprehensive circulatory metabolomics in ME/CFS - Global Metabolites

This data is adapted from the publication: Germain A, Barupal DK, Levine SM, Hanson MR. Comprehensive circulatory metabolomics in ME/CFS reveals disrupted metabolism of acyl...
- MECFSnet
- has data file
- has phenotype file
- publication-adapted

Metabolic profiling of a ME/CFS syndrome discovery cohort

This data is adapted from the publication: Germain A, Ruppert D, Levine SM, Hanson MR. Metabolic profiling of a myalgic encephalomyelitis/chronic fatigue syndrome discovery...
- has data file
- has phenotype file
- publication-adapted

Comprehensive circulatory metabolomics in ME/CFS - Lipidomics

This data is adapted from the publication: Germain A, Barupal DK, Levine SM, Hanson MR. Comprehensive circulatory metabolomics in ME/CFS reveals disrupted metabolism of acyl...
- MECFSnet
- has data file
- has phenotype file
- publication-adapted

ME/CFS case-control plasma proteomics (Partially Normalized)

Plasma proteomics of 20 ME/CFS patients and 20 controls containing 4,790 unique human proteins obtained through somalogic's aptamer-based assay. This dataset contains the...
- has data file
- has phenotype file
- proteomics
- publication-adapted

Eukaryotes in the gut microbiota in myalgic encephalomyelitis/chronic fatigue...

This data has been adapted from the publication: Mandarano AH, Giloteaux L, Keller BA, Levine SM, Hanson MR. Eukaryotes in the gut microbiota in myalgic...

Mitochondrial DNA variants correlate with symptoms in ME/CFS

This data was adapted from the publication: Billing-Ross, P., Germain, A., Ye, K. et al. Mitochondrial DNA variants correlate with symptoms in myalgic encephalomyelitis/chronic...
- CFI
- Illumina MiSeq
- mitochondrial DNA
- no data file
- no phenotype file
- publication-adapted

Reduced diversity and altered composition of the gut microbiome in individual...

The data is adapted from the publication: Giloteaux, L., Goodrich, J.K., Walters, W.A. et al. Reduced diversity and altered composition of the gut microbiome in individuals with...
- no data file
- no phenotype file
- publication-adapted

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