-
Cardiopulmonary and metabolic responses during a 2-day CPET in ME/CFS
Keller et al. collected and analyzed cardiopulmonary exercise testing (CPET) data gathered over two days from 84 individuals with ME/CFS and 71 sedentary controls. Within this... -
ME/CFS patients exhibit altered T cell metabolism and cytokine associations – plasma cytokines
Mandarano et al. investigated immune metabolism in ME/CFS. T cell metabolism was assayed in 53 people with ME/CFS and 45 healthy controls. A subset of the cohort (i.e., 38 cases... -
Dysregulation of extracellular vesicle protein cargo in female ME/CFS cases and sedentary controls in response to maximal exercise
As part of a research grant supported by NIH NINDS/OD/NIDA/NHLBI/NHGRI through NINDS U54NS105541 to the Cornell Center for Enervating Neuroimmune Disease and by a private donor,... -
Altered Fatty Acid Oxidation in Lymphocyte Populations of ME/CFS - flow mean intensity
Seahorse flux analysis and flow cytometry were performed on case and control immune cell subtypes. PBMCs were separated into NK and CD4 and CD8 T cell populations. The results... -
Survey of Anti-Pathogen Antibody Levels in ME/CFS
Plasma antibodies to 122 different pathogen antigens were evaluated in a case-control comparison including 103 individuals. The cohort of 59 ME/CFS and 44 healthy controls... -
Urine Metabolomics Exposes Anomalous Recovery after Maximal Exertion in Female ME/CFS Patients
Pilot urine metabolomics study that analyzed Metabolon data generated from 10 people with ME/CFS and 8 healthy sedentary controls. All participants are female. Data was compared... -
Urine Metabolomics Exposes Anomalous Recovery after Maximal Exertion in Female ME/CFS Patients - raw
Pilot urine metabolomics study that analyzed Metabolon data generated from 10 people with ME/CFS and 8 healthy sedentary controls. All participants are female. Data was compared... -
Altered Fatty Acid Oxidation in Lymphocyte Populations of ME/CFS - flux measurements
Seahorse flux analysis and flow cytometry were performed on case and control immune cell subtypes. PBMCs were separated into NK and CD4 and CD8 T cell populations. The results... -
Altered Fatty Acid Oxidation in Lymphocyte Populations of ME/CFS - flow median intensity
Seahorse flux analysis and flow cytometry were performed on case and control immune cell subtypes. PBMCs were separated into NK and CD4 and CD8 T cell populations. The results... -
Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/chronic fatigue syndrome: a pilot study - plasma cyt...
Giloteaux et al. performed a pilot study to investigate the cytokine content of extracellular vesicles (EVs) in ME/CFS. Plasma cytokines were measured in 38 females (19 ME/CFS... -
Recovery from Exercise in Persons with ME/CFS
Moore et al. studied 84 people with ME/CFS and 60 controls using a self-reported symptom severity questionnaire. Both female and male participants from three different test... -
Multiomic analyses distinguish ME/CFS cases from controls - EV cytokines
As part of a collaborative project with the Center for Solutions for ME/CFS, Ludovic Giloteaux isolated extracellular vesicles (EVs) from 98 (49 ME/CFS and 49 control) Chronic... -
Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/chronic fatigue syndrome: a pilot study - EV cytokines
Giloteaux et al. performed a pilot study to investigate the cytokine content of extracellular vesicles (EVs) in ME/CFS. EV cytokines were measured in 37 females (19 ME/CFS and... -
ME/CFS case-control DNA methylation study GSE111183
Trivedi et al. (2018) conducted a case-control study with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) on 25 participants (13 ME/CFS cases and 12 healthy... -
Plasma metabolomics reveals disrupted response and recovery following maximal exercise in ME/CFS
Over 1,100 plasma metabolites were measured and analyzed in 60 ME/CFS and 45 healthy control participants. Each cohort consisted of both females and males. This longitudinal... -
ME/CFS case-control DNA methylation study GSE93266
de Vega et al. (2017) profiled DNA methylation among 75 myalgic encephalomyelitis/chronic fatigue syndrome cases and healthy controls. Methylation profiling for this dataset was... -
ME/CFS case-control DNA methylation study GSE59489
de Vega et al. (2014) conducted a case-control study with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) on 24 participants (12 ME/CFS cases and 12 healthy... -
Prospective Biomarkers from Plasma Metabolomics of ME/CFS
Adapted from the paper Germain A, Ruppert D, Levine SM, Hanson MR. Prospective Biomarkers from Plasma Metabolomics of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome... -
Profile of circulating microRNAs in myalgic encephalomyelitis and their relation to symptom severity, and disease pathophysiology
Adapted from Nepotchatykh, E., Elremaly, W., Caraus, I. et al. Profile of circulating microRNAs in myalgic encephalomyelitis and their relation to symptom severity, and disease...
