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ME/CFS patients exhibit altered T cell metabolism and cytokine associations – plasma cytokines
Mandarano et al. investigated immune metabolism in ME/CFS. T cell metabolism was assayed in 53 people with ME/CFS and 45 healthy controls. A subset of the cohort (i.e., 38 cases... -
Dysregulation of extracellular vesicle protein cargo in female ME/CFS cases and sedentary controls in response to maximal exercise
As part of a research grant supported by NIH NINDS/OD/NIDA/NHLBI/NHGRI through NINDS U54NS105541 to the Cornell Center for Enervating Neuroimmune Disease and by a private donor,... -
Altered Fatty Acid Oxidation in Lymphocyte Populations of ME/CFS - flow mean intensity
Seahorse flux analysis and flow cytometry were performed on case and control immune cell subtypes. PBMCs were separated into NK and CD4 and CD8 T cell populations. The results... -
Urine Metabolomics Exposes Anomalous Recovery after Maximal Exertion in Female ME/CFS Patients - raw
Pilot urine metabolomics study that analyzed Metabolon data generated from 10 people with ME/CFS and 8 healthy sedentary controls. All participants are female. Data was compared... -
Altered Fatty Acid Oxidation in Lymphocyte Populations of ME/CFS - flux measurements
Seahorse flux analysis and flow cytometry were performed on case and control immune cell subtypes. PBMCs were separated into NK and CD4 and CD8 T cell populations. The results... -
Altered Fatty Acid Oxidation in Lymphocyte Populations of ME/CFS - flow median intensity
Seahorse flux analysis and flow cytometry were performed on case and control immune cell subtypes. PBMCs were separated into NK and CD4 and CD8 T cell populations. The results... -
Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/chronic fatigue syndrome: a pilot study - plasma cyt...
Giloteaux et al. performed a pilot study to investigate the cytokine content of extracellular vesicles (EVs) in ME/CFS. Plasma cytokines were measured in 38 females (19 ME/CFS... -
Recovery from Exercise in Persons with ME/CFS
Moore et al. studied 84 people with ME/CFS and 60 controls using a self-reported symptom severity questionnaire. Both female and male participants from three different test... -
Multiomic analyses distinguish ME/CFS cases from controls - EV cytokines
As part of a collaborative project with the Center for Solutions for ME/CFS, Ludovic Giloteaux isolated extracellular vesicles (EVs) from 98 (49 ME/CFS and 49 control) Chronic... -
Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/chronic fatigue syndrome: a pilot study - EV cytokines
Giloteaux et al. performed a pilot study to investigate the cytokine content of extracellular vesicles (EVs) in ME/CFS. EV cytokines were measured in 37 females (19 ME/CFS and... -
ME/CFS case-control DNA methylation study GSE111183
Trivedi et al. (2018) conducted a case-control study with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) on 25 participants (13 ME/CFS cases and 12 healthy... -
Genome-epigenome interactions associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome GSE156792
Adapted from Herrera, S., de Vega, W. C., Ashbrook, D., Vernon, S. D., & McGowan, P. O. (2018). Genome-epigenome interactions associated with Myalgic... -
ME/CFS case-control DNA methylation study GSE93266
de Vega et al. (2017) profiled DNA methylation among 75 myalgic encephalomyelitis/chronic fatigue syndrome cases and healthy controls. Methylation profiling for this dataset was... -
ME/CFS case-control DNA methylation study GSE59489
de Vega et al. (2014) conducted a case-control study with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) on 24 participants (12 ME/CFS cases and 12 healthy... -
ME/CFS case-control RNA expression study following exercise GSE128078
Bouquet et al. (2019) performed RNA sequencing on female ME/CFS patients and match controls pre- and post- cardiopulmonary exercise stress testing to identify potential gene... -
ME/CFS case-control plasma proteomics (Fully Normalized)
Plasma proteomics of 20 ME/CFS patients and 20 controls containing 4,790 unique human proteins obtained through somalogic's aptamer-based assay.This dataset contains the fully... -
Comprehensive circulatory metabolomics in ME/CFS - Global Metabolites
This data is adapted from the publication: Germain A, Barupal DK, Levine SM, Hanson MR. Comprehensive circulatory metabolomics in ME/CFS reveals disrupted metabolism of acyl... -
Metabolic profiling of a ME/CFS syndrome discovery cohort
This data is adapted from the publication: Germain A, Ruppert D, Levine SM, Hanson MR. Metabolic profiling of a myalgic encephalomyelitis/chronic fatigue syndrome discovery... -
ME/CFS case-control miRNA expression study GSE70371
Petty et al. (2016) performed a microarray-based differential expression analysis of miRNA on ME/CFS patients and matched controls. -
ME/CFS case-control miRNA expression study GSE141770 - PBMC
Almenar-Pérez et al. (2020) conducted a study on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) where miRNA profiles were analyzed using array technology in...
